Histopathologic Studies of Pigmented Nevi in Children*†
نویسندگان
چکیده
منابع مشابه
The physiology of pigmented nevi.
Melanocytes are pigment-producing cells derived from the neural crest. These specialized exocrine cells produce melanin, which is packaged and dispersed to neighboring keratinocytes in organelles called melanosomes. Within the melanocyte, tyrosine is converted to dopa, and then dopaquinone via the bifunctional enzyme tyrosinase. Dopaquinone is oxidized further to form the pigment melanin. Each ...
متن کاملDifferentiation of pigmented Spitz nevi and Reed nevi by integration of dermatopathologic and dermatoscopic findings
BACKGROUND It is unclear whether pigmented Spitz and Reed nevi are distinct morphologic entities or part of the spectrum of Spitz nevi. METHODS In a retrospective observational study we analyzed dermatopathologic slides of 22 cases with clinical and dermatoscopic features indicative of pigmented Spitz or Reed nevus in a blinded fashion according to predefined criteria and subsequently correla...
متن کاملDevelopment of multiple pigmented nevi within segmental nevus depigmentosus.
Nevus depigmentosus is a stable and well-circumscribed congenital hypomelanosis that may be in an isolated, dermatomal or systemic form. An 18-yr-old Korean man with segmental nevus depigmentosus developed multiple pigmented nevi which were present only within the confines of the leukoderma. Histologic and electron microscopic studies rendered a diagnosis of nevus depigmentosus with dysplastic ...
متن کاملDermoscopy of pigmented Spitz and Reed nevi: the starburst pattern.
Richard Marchell, MD; Ashfaq A. Marghoob, MD; Ralph P. Braun, MD; Giuseppe Argenziano, MD; Departments of Dermatology, Stony Brook University Hospital, Stony Brook, NY (Dr Marchell), University Hospital Geneva, Geneva, Switzerland (Dr Braun), and Second University of Naples, Naples, Italy (Dr Argenziano); and the Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, NY (Dr Marg...
متن کاملCongenital giant pigmented nevi: Clinical features and risk of malignancy
MJ Weinberg, M Al-Qattan, RM Zuker, HG Thomson, WK Lindsay. Can J Plast Surg 1996;4(2):94-98. There is general agreement that congenital giant pigmented nevi (CGPN) are precursors to malignant melanoma; however, the magnitude of the risk of malignant transformation is the subject of wide controversy. The goal of this study was to present the authors’ experience with CGPN and more specifically t...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1953
ISSN: 0022-202X
DOI: 10.1038/jid.1953.8